(adjective)
completely helpless and overcome with exhaustion or distress, lacking power, vitality, or the will to rise;
e.g. They were prostrate from exhaustion at the end of their journey.
(adjective)
in botany, growing or trailing along on the ground;
e.g. These berries grow on prostrate vines that cover the surface of the ground.
(verb)
to place or position oneself such that one is lying flat on the ground with one's face downwards, typically as a gesture of respect, humility, or submissiveness;
e.g. He was expected to prostrate himself before the religious leader.
(verb)
to reduce someone to a state of helplessness, submission, or extreme physical exhaustion/weakness;
e.g. These severe headaches prostrate him at least once every week.